Leader, Applied Science & Technology
Dr. Chilcoat leads the Applied Science & Technology (AST) organization at Corteva Agriscience. His responsibilities include vector construction, protein engineering, genome engineering (traditional transformation and use of CRISPR/Cas9 technology), genomics, greenhouses/controlled environments, high-throughput macromolecular analysis, protein production, analytic chemistry, and chemometrics (including remote sensing). AST supports the entire R&D portfolio and provides DNA sequencing for all of Corteva. AST includes more than 300 researchers at multiple global sites.
AST is a leader in the development and deployment of CRISPR/Cas9 based genome editing technology.
Recent highlights include:
- Use of CRISPR/Cas to improve grain composition and drought tolerance in maize
- Discovery of Cas9 proteins with novel properties
- Development of a new off-site detection method
- The first demonstration of RNP based (DNA free) editing in crop plants
Prior to taking his current role in June 2011, Doane was CEO and cofounder of an anti-infective biotech focused on the human microbiome, Cobax Biopharma. Before that he was Senior Director of Sales Operations at Replidyne, a public biotechnology company. He previously was an associate partner with McKinsey and Company in Chicago and Los Angeles, with a practice that focused on life science companies: agriculture, biochemical reagents, and pharma/biotech. Doane received his B.A. in Biology from Grinnell College and his Ph.D. in Molecular Genetics and Cell Biology from the University of Chicago.