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Elaine R. Mardis

Elaine R. Mardis

Professor of Pediatrics, Ohio State University College of Medicine
Co-Director, Institute for Genomic Medicine, Research Institute, Nationwide Children’s Hospital
Columbus, OH

Elaine R. Mardis, PhD is a professor of pediatrics at the Ohio State University College of Medicine and Co-Director of the Institute for Genomic Medicine, at the Research Institute of Nationwide Children’s Hospital, both in Columbus, Ohio.. Prior to moving to Ohio, Dr. Mardis spent twenty three years at Washington University School of Medicine in St. Louis, Missouri, where she was co-director of the McDonnell Genome Institute (2002-2016), co-leader of the Breast Cancer Research Program at the Alvin J. Siteman Cancer Center (2014-16), Robert E. and Louise F. Dunn Distinguished Professor of Medicine (2014-16), and Professor of Genetics (2011-16).

Dr. Mardis’s research focuses on the application of next generation sequencing to characterize cancer genomes and using these data to support therapeutic decision making. She played a pivotal role in the sequencing of the Human Genome Project. She is an internationally recognized expert in cancer genomics, having been one of the team leaders to first sequence and analyze a whole cancer genome using next generation sequencing methods. She has characterized multiple tumour types in both pediatric and adult cancers.  More recently, she has worked with colleagues to use genomic data to design novel, personalized vaccines for individual patients.  Beyond cancer genomics discoveries, Dr. Mardis is leading efforts to facilitate the translation of basic science discoveries about human genetic diseases into clinical settings.

Dr. Mardis holds both a BS (1984) and a PhD (1989) from the University of Oklahoma. She is the recipient of the Translational Medicine Award from the Scripps Research Institute (2010), the George Engelmann Interdisciplinary Award from the St. Louis Academy of Science (2012) and the Morton K. Schwartz Award (2016) from the American Association of Clinical Chemistry. 

Dr. Mardis was elected to membership in the U.S. National Academy of Medicine in 2019.