Senior Investigator, National Human Genome Research Institute, NIH
Chief, Translational and Functional Genomics Branch
Head, Microbial Genomics Section
Julie Segre, Ph. D. is a Senior Investigator at the National Human Genome Research Institute, NIH. Her research focuses on microbial genomics, investigating both hospital pathogens and the diversity of commensal skin organisms. Segre’s research integrates DNA sequence technology, algorithm development and diagnostic clinical microbiology. Segre has published extensively with 30 research articles (19 as senior author) and 5 review articles in the last 5 years in journals including Science, Nature, Science Translational Medicine, PNAS, Genome Biology and Genome Research.
Segre’s research has defined the normal human skin bacterial and fungal communities, enabling studies of alterations associated with pediatric atopic dermatitis and primary immunodeficiency. Segre’s research also focused on integrating whole genome sequencing of hospital pathogens both to study nosocomial transmission and to develop a national surveillance network.
Segre received the 2013 Service to America Medal, together with NIH Clinical Center epidemiologist Tara Palmore, for deploying genomic sequencing to guide hospital outbreak containment. Segre received her B.A. from Amherst College in 1987, graduating Phi Beta Kappa and summa cum laude in mathematics. She obtained her PhD in 1996 in Genetics from MIT, advised by Eric S. Lander, PhD and received postdoctoral training in skin biology mentored by Elaine Fuchs, PhD. Segre was recruited as a new investigator to NHGRI/NIH in 2000 and received tenure in 2007. Segre was elected to the Board of Trustees of Amherst College in 2011.