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Applied Bioinformatics of Cis-regulation for Disease Exploration (ABC4DE)

2012 Bioinformatics and Computational Biology Competition
Genome Centre(s):
Genome British Columbia
Project Leader(s):
Wyeth Wasserman (University of British Columbia)
Fiscal Year Project Launched: 
Project Description: 

The goal of personalized medicine is to treat patients in the manner that is most appropriate for each individual. Before this can happen, doctors will need software that can perform detailed high-speed and low-cost analyses of patients' specific genetic mutations.

Dr. Wyeth Wasserman is developing software that will understand and categorize the pieces of DNA that help turn genes on or off. These small sequences of DNA are spread throughout the human genome and serve a critical role in controlling when and where genes are turned on. Mutations in these on/off switches can cause birth defects, disease risk and adverse drug reactions. The software will help physicians analyze patients’ genetic mutations and pave the way for personalized medicine.