The sequencing and bioinformatics analysis platforms at Canada’s Michael Smith Genomic Sciences Centre have operated as a Genome Canada platform since 2001. In that time, its technical ability to deliver successful collaborations and service arrangements has led to its involvement in 705 grants and contracts totaling more than $875 million, and supporting the work of more than 1,500 researchers, both nationally and internationally. Among its contributions are reference genomes for bovine, spruce, poplar, Atlantic salmon and Chardonnay grape; human reference epigenomes; and human, mouse and zebrafish cDNA reference transcriptomes. Its whole-genome analysis is being used to inform personalized treatment planning for cancer patients. The platform also provides training to technical and support staff, as well as graduate and postdoctoral research trainees.
With this Genome Canada funding, the platform will expand both its personnel and its service offerings, including both new technology development and assessment and data processing and bioinformatics analysis. It will also develop a bioinformatics virtual machine to provide researchers with the computational tools they need to interact with, visualize and analyze data. This funding will also enable the GSC to grow its capacity for genomics services through the collaborative partnership with University of British Columbia.