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Rapid, accessible genome assembly using long read sequencing

Status: 
Active
Competition: 
2015 Bioinformatics and Computational Biology B/CB
Sector: 
Health
Agriculture and Agri Food
Environment
Genome Centre(s):
Ontario Genomics
Project Leader(s):
Jared Simpson (University of Toronto and Ontario Institute for Cancer Research)
Fiscal Year Project Launched: 
2016-2017
Project Description: 

DNA sequencing technology has progressed from sequencing single reference genomes at great cost and time, to the current era of inexpensive, high-throughput short read sequencing. The emerging “third generation” of DNA sequencing technology offers the prospect of putting long read genome sequencing in the hands of more researchers and enabling new applications, through portable instruments that will decentralize sequencing technology.

Dr. Jared Simpson of the University of Toronto is developing robust and efficient genome assembly software that is easy to use, to match the capabilities of these emerging sequencing instruments. The software will target biologists and other end users of sequencing who don’t have substantial bioinformatics expertise.