CENTRES SECTOR LEADERS ORGANIZATIONS TITLE TOTAL FUNDING GENOME CANADA CONTRIBUTION Genome British Columbia Health Richard Harrigan Julio Montaner British Columbia Centre for Excellence in HIV/ AIDS, St. Paul’s Hospital Viral and Human Genetic Predictors of Response to HIV Therapies $4,758,743 $1,103,367 Génome Québec Health Nada Jabado Jacek Majewski Tomi Pastinen McGill University Health Centre The ICHANGE (International CHildhood Astrocytomas iNtegrated Genomics and Epigenomics) Consortium $5,122,390 $1,230,661 Genome Alberta Health Christopher McCabe Tania Bubela University of Alberta PACE'Omics: Personalized, accessible, cost-effective applications of 'omics technologies $4,502,084 $1,049,258 Genome British Columbia Genome Alberta Health Andrew Penn Christoph Borchers Shelagh Coutts Vancouver Island Health Authority Reducing Stroke Burden with Hospital-Ready Biomarker Test for Rapid TIA Triage $9,634,996 $4,755,969 Génome Québec Health Claude Perreault Denis-Claude Roy Université de Montréal Hôpital Maisonneuve- Rosemont Personalized Cancer Immunotherapy $13,486,784 $2,409,386 Génome Québec Health John Rioux Alain Bitton Montreal Heart Institute IBD Genomic Medicine Consortium (iGenoMed): Translating genetic discoveries into a personalized approach to treating the inflammatory bowel diseases $9,966,018 $2,460,036 Génome Québec Genome British Columbia Health François Rousseau Sylvie Langlois Université Laval PEGASUS: Personalized genomics for prenatal aneuploidy screening using maternal blood $10,525,682 $2,475,010 Génome Québec Health Guy Sauvageau Josée Hébert Institute for Research in Immunology and Cancer Innovative Chemogenomic Tools to Improve Outcome in Acute Myeloid Leukemia $11,325,631 $4,908,515 Ontario Genomics Health Stephen Scherer Peter Szatmari The Hospital for Sick Children Autism Spectrum Disorders: Genome to outcomes $9,979,998 $2,479,999 Génome Québec Health Jacques Simard Bartha Maria Knoppers Université Laval Personalized Risk Stratification for Prevention and Early Detection of Breast Cancer $11,761,246 $2,732,295 Genome British Columbia Health Don Sin Raymond Ng St. Paul’s Hospital, University of British Columbia PROOF Centre for Excellence Clinical Implemetation and Outcomes Evaluation of Blood-Based Biomarkers for COPD Management $7,100,000 $1,700,000 Ontario Genomics Health Lincoln Stein Tony Godfrey Ontario Institute for Cancer Research Early Detection of Patients at High Risk of Esophageal Adenocarcinoma $3,240,865 $795,272 Ontario Genomics Health Alain Stintzi Dave Mack University of Ottawa The Microbiota at the Intestinal Mucosa-Immune Interface: A gateway for personalized health $2,961,445 $716,360 Genome Canada Annual Report 2016-17 30 LARGE-SCALE science