Genome Canada Annual Report 2016-17 35 CENTRES SECTOR LEADERS ORGANIZATIONS TITLE TOTAL FUNDING GENOME CANADA CONTRIBUTION Ontario Genomics Health Michael Brudno Gary Bader The Hospital for Sick Children MedSavant: An integrative framework for clinical and research analysis of human genomes $998,546 $499,273 Ontario Genomics Health Jordan Lerner-Ellis Matthew Lebo Mount Sinai Hospital Development of a Unified Canadian Clinical Genomic Database as a Community Resource for Standardizing and Sharing Genetic Interpretations $1,000,000 $500,000 Génome Québec Health Jerome Waldispuhl Mathieu Blanchette McGill University A Development and Deployment Platform for Citizen Science Games in Genomics $249,318 $62,329 DISRUPTIVE INNOVATION IN GENOMICS Genome British Columbia All Fraser Hof University of Victoria A Chemo-Affinity Toolkit for Methylation Proteomics $238,800 $238,800 Genome British Columbia All Sohrab Shah Cydney Nielsen University of British Columbia Reimagining Genome Browsing for the Era of Single Cell Genomics $250,000 $250,000 Genome British Columbia All Wyeth Wasserman University of British Columbia GNOmics: Graphs 'n' omics $250,000 $250,000 Génome Québec All Santiago Costantino Claudia Kleinman McGill University Laser Assisted Single-Cell Genomics $250,000 $250,000 Génome Québec All David Juncker McGill University Single Exosome Multi-Omic Analysis $249,999 $249,999 Génome Québec All Eric Lécuyer Mathieu Blanchette Jérome Waldispuhl Institut de recherches cliniques de Montréal The RNA Zipcode Discovery Pipeline: Emerging tools for targeting therapeutic molecules at subcellular resolution $250,000 $250,000 Génome Québec All Mark Trifiro Andrew Kirk McGill University Plasmonic PCR: Rapid diagnostics through plasmonics $249,976 $249,976 Génome Québec Ontario Genomics All Michael Tyers Gerard Wright Université de Montréal A Cell Microfactory Platform for In Vivo Biosynthesis and Delivery of Genetically Encoded Natural Products and Synthetic Antibodies $249,358 $249,358 Ontario Genomics All Charles Boone Jason Moffat University of Toronto AbSyn Technology for Identification of Synergistic Cancer Therapeutics $249,389 $249,389 Ontario Genomics All James Dowling Michael Brudno The Hospital for Sick Children RNA-seq in Patient-Derived Ex-Vivo Models: Genetic diagnostics beyond whole exomes $250,000 $250,000 Ontario Genomics All Andrew Emili University of Toronto Massively Parallel Single Molecule Protein Sequencing in Situ $250,000 $250,000 Ontario Genomics All Daniel Figeys Alain Stintzi University of Ottawa RapidAIM: A high-throughput assay of individual microbiome $250,000 $250,000 Ontario Genomics All Turlough Finan McMaster University Development of Advanced Genetic Toolbox for Sinorhi- zobium Meliloti to Enable Genome Scale Engineering $250,000 $250,000