Genome Canada Annual Report 2016-17 36 CENTRES SECTOR LEADERS ORGANIZATIONS TITLE TOTAL FUNDING GENOME CANADA CONTRIBUTION Ontario Genomics All Peter Krell Daniel Doucet University of Guelph Cell Biosensors for Rapid Screening of Insect Attractants $233,901 $233,901 Ontario Genomics All Stephen Scherer Si Lok The Hospital for Sick Children Economical High Throughput De Novo Whole Genome Assembly $241,467 $241,467 Ontario Genomics All Igor Stagljar University of Toronto Development of SIMPL, a Novel Protein-Protein Interaction Assay based on Split Intein for Biomedical Research $250,000 $250,000 Ontario Genomics All Vincent Tabard- Cossa University of Ottawa Solid-State Nanopore-based Quantification of Low- Abundance Biomarkers $250,000 $250,000 Ontario Genomics All Michael Taylor Rama Khokha The Hospital for Sick Children Functional Genomics in Human Cells for Drivers of Lethal Metastatic Human Cancers $250,000 $250,000 Ontario Genomics All Aaron Wheeler Elena Kolomietz University of Toronto Development of a Digital Microfluidic Platform to Identify and Target Single Cells from a Heterogeneous Cell Population for Lyses in an Ultra-Low Volume $250,000 $250,000 Ontario Genomics Michael Wilson Adam Shlien University of Toronto SANGRE Systematic Analysis of Blood Gene Regulation by Sequencing – Bringing RNA- seq to clinical diagnostics $249,934 $249,934 Genome British Columbia All Christoph Borchers Albert Sickmann University of Victoria Replacing Immunoassays with MS-based Technology: Quantitative proteomics kits enabling deep molecular phenotyping of the mouse $3,865,231 $999,695 Genome British Columbia All Carl Hansen University of British Columbia Next Generation Immune Profiling Technology based on Microfluidic Single Cell Analysis $2,993,509 $991,185 Genome British Columbia All Marco Marra Robin Coope BC Cancer Agency Automated Tumour Pathology $409,858 $101,559 Ontario Genomics All Sachdev Sidhu University of Toronto Synthetic Inhibitors of Ubiquitin-Binding Cancer Targets $3,009,018 $1,000,000 Ontario Genomics All Igor Stagljar University of Toronto The Mammalian Membrane Two-Hybrid MaMTH Assay – An advanced proteomics technol- ogy for biomedical research $3,000,000 $1,000,000 LEADING-EDGE technology